Tuesday, June 25, 2013

Murder trial begins in earnest in Florida's Trayvon Martin case

By Tom Brown and Barbara Liston

SANFORD, Florida (Reuters) - The murder trial of George Zimmerman, whose fatal shooting of unarmed black teenager Trayvon Martin triggered nationwide protests last year, begins in earnest on Monday in a Florida courtroom.

Opening statements from lawyers outlining the basic facts in the case, and what they believe the evidence will show, are set to begin at 9 a.m. EDT.

This follows two weeks of jury selection which ended last week with a panel of six female jurors chosen to decide Zimmerman's fate. Due to blanket media coverage the judge ordered the jury sequestered for the duration of the trial.

Zimmerman, who is 29 and part Hispanic, was the neighborhood watch captain in a gated community in Sanford at the time of the killing on February 26, 2012. He has pleaded innocent to the charge of second-degree murder and could face life imprisonment if convicted.

Martin, 17, was a student at a Miami-area high school and a guest of one of the homeowners in the Retreat at Twin Lakes community. He was walking back to the residence after buying snacks at a nearby convenience store when he was shot in the chest during a confrontation with Zimmerman.

Because Sanford police initially failed to arrest Zimmerman, on grounds that he acted in self-defense, many saw the killing as an example of second-class treatment of black victims in the U.S. criminal justice system.

That set off civil rights rallies and cries of injustice across the United States throughout much of last year. It also threw a spotlight on gun use and Florida's controversial self-defense laws.

Much of what happened during Martin's fatal encounter with Zimmerman is still a mystery. Neighbors who witnessed the scuffle and the fatal shot, albeit on a rainy night, are expected to testify.

Zimmerman claims Martin was the aggressor, but Assistant State Attorney Bernie de la Rionda, who is the lead prosecutor, says the younger man would be alive today had he not been profiled by Zimmerman as "a real suspicious guy."

Setting the stage for a possible fiery opening to the trial, presiding Seminole County Judge Debra Nelson overruled objections from the defense last week and said prosecutors could use such inflammatory terms as "vigilante" and "wannabe cop" in referring to Zimmerman.

She also ruled that prosecutors could say Zimmerman "profiled" Martin and "confronted" him, language suggesting that he initiated the altercation that led to Martin's death.

There is a high bar for the prosecution in a case that will center on Florida's aggressive self-defense laws, however. Under Florida's Stand Your Ground law, which was approved in 2005 and has since been copied by about 30 other states, people fearing for their lives can use deadly force without having to retreat from a confrontation, even when it is possible.

In instructions on "justifiable use of deadly force," that Nelson read to potential jurors last week, she noted that anyone in fear of grievous bodily harm or death is entitled to shoot and kill an assailant rather than back down.

"The danger facing the defendant need not have been actual," Nelson said, suggesting that mere perception of "danger" was enough to make it reality.

"If the defendant was not engaged in an unlawful activity, and was attacked in any place where he had a right to be, he had no duty to retreat and a right to stand his ground and meet force with force, including deadly force, if he reasonably believed that it was necessary do so," Nelson said.

(Writing by Tom Brown; editing by David Adams and Jackie Frank)

Source: http://news.yahoo.com/murder-trial-begins-earnest-floridas-trayvon-martin-case-050411255.html

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Monday, June 24, 2013

South Africa: Nelson Mandela in critical condition

JOHANNESBURG (AP) ? Nelson Mandela's health has deteriorated and he is now in critical condition, the South African government said Sunday.

The office of President Jacob Zuma said in a statement that he had visited the 94-year-old anti-apartheid leader at a hospital Sunday evening and was informed by the medical team that Mandela's condition had become critical in the past 24 hours.

"The doctors are doing everything possible to get his condition to improve and are ensuring that Madiba is well-looked after and is comfortable. He is in good hands," Zuma said in the statement, using Mandela's clan name.

Zuma also met Graca Machel, Mandela's wife, at the hospital in Pretoria and discussed the former leader's condition, according to the statement. Zuma was accompanied on the visit by Cyril Ramaphosa, the deputy president of the country's ruling party, the African National Congress.

Mandela was jailed for 27 years under white racist rule and released in 1990. He then played a leading role in steering the divided country from the apartheid era to democracy, becoming South Africa's first black president in all-race elections in 1994. He was hospitalized on June 8 for what the government said was a recurring lung infection.

In Sunday's statement, Zuma also discussed the government's acknowledgement a day earlier that an ambulance carrying Mandela to the hospital two weeks ago had engine trouble, requiring the former president to be transferred to another ambulance for his journey to the hospital.

"There were seven doctors in the convoy who were in full control of the situation throughout the period. He had expert medical care," Zuma said. "The fully equipped military ICU ambulance had a full complement of specialist medical staff including intensive care specialists and ICU nurses. The doctors also dismissed the media reports that Madiba suffered cardiac arrest. There is no truth at all in that report."

Mandela is seen by many around the world as a symbol of reconciliation, and Zuma appealed to South Africans and the international community to pray for the ailing ex-president, his family and the medical team attending to him.

The ruling party expressed concern about the deterioration in Mandela's health.

"We welcome the work being done by The Presidency to ensure that South Africans and people of the world are kept informed on the state of Madiba's health," the party said. "The African National Congress joins The Presidency in calling upon all of us to keep President Mandela, his family and his medical team in our thoughts and prayers during this trying time."

Prior to Zuma's statement late Sunday, reports from the government, former President Thabo Mbeki and a grandson of Mandela had indicated that the health of Mandela was improving, even though he has been in the hospital for treatment several times in recent months. Mandela last made a public appearance in 2010, and has become increasingly frail in recent years.

On April 29, state television broadcast footage of a visit by Zuma and other leaders of the African National Congress to Mandela's home. Zuma said at the time that Mandela was in good shape, but the footage ? the first public images of Mandela in nearly a year ? showed him silent and unresponsive, even when Zuma tried to hold his hand.

Source: http://news.yahoo.com/south-africa-nelson-mandela-critical-condition-201653072.html

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Martin Truex Jr. snaps 218-race losing streak

SONOMA, Calif. (AP) ? Martin Truex Jr. snapped a 218-race winless streak with an easy victory Sunday on the road course at Sonoma Raceway.

It was just the second win of Truex's career, first since Dover in 2007. It put Michael Waltrip Racing in Victory Lane for the second year in a row after Clint Bowyer won here last season.

Truex worked his way to the front and used strategy to stay with the leaders. He then pulled away after the final restart and built a healthy lead of more than six seconds over Juan Pablo Montoya, who was running second until he ran out of gas on the final lap.

"I'm ecstatic. But I'm not exactly sure how that happened," said Truex, who admitted he wasn't pleased with his car following Friday's practices. "The car was just phenomenal all day long and once I was near the front and didn't have to run the car 110 percent, it just would stay with me on the long runs and I was able to drive away from everyone."

Montoya, who came into the weekend knowing if he didn't win he would at least have a huge points day, dropped all the way to 34th after having to coast to the finish. He took a shortcut to skip the final turn, drifted to the finish line and parked. He then walked back to the garage, annoyed his Chip Ganassi Racing team never told him to save fuel.

"We've got tools to prevent things like that from happening," Montoya said.

"I don't know if all the fuel didn't go," Montoya said. "This is what we've been doing all year. We all work together and we're all trying to do the best we can. Half the reason we're 20-something in points ? we're not 20-something in points because we're not running fast. We're 20-something in points because we had a lot of mechanical problems and days like this we throw them away."

Crew chief Chris Heroy was perplexed about the shortage.

"We don't know what happened ? we were on the same strategy as (Truex)," Heroy said through a team spokeswoman. "We're going to go back to the shop and figure it out."

Montoya got little sympathy from Kyle Busch, who was spun by Montoya early in the race when Montoya drove too deep into a corner and wheel-hopped over a curb.

"Awww. My heart melts for @jpmontoya who ran out of gas," Busch tweeted moments after the race.

Jeff Gordon finished second a week after he was wrecked six laps into the race at Michigan, but felt like he might have had a chance to win if he had not already committed to pit seconds before a caution came out early in the race.

"I mean, I really do think we had a shot winning this race. We had a tremendous car," Gordon said. "I knew we were screwed. There was nothing I could do; I was hard on the brakes, fully committed. I couldn't turn away from it, I just knew we had to eat it and go on, and that's what we did."

Carl Edwards was third, followed by Kurt Busch, who climbed back from a pair of speeding penalties.

"Yeah, we were fast, even on pit road. Twice," Busch laughed. "I messed-up, flat-out. I didn't hit my tachometer right and I was speeding both times. It was one of those where I'm like, how does that happen? I just put myself in a position that was poor trying to get too much on pit road."

Bowyer wound up fifth in a strong day for the MWR Toyotas.

Kasey Kahne was sixth and followed by Marcos Ambrose, who was extremely disappointed he didn't win a race in which he was heavily favored.

"It's OK. We got a top-10 out of it," Ambrose said. "I wanted to win. Of course I wanted to win, but that's the way it goes."

Greg Biffle was eighth and followed by Jimmie Johnson and Kevin Harvick in the top 10.

The race got off to an inauspicious start before it even began with a pit road accident, a mechanical issue for Jacques Villeneuve and an oil line failure for Bobby Labonte.

The accident occurred as the cars were headed onto the track and David Reutimann stopped his car on pit road. Alex Kennedy stopped behind Reutimann, and Paulie Harraka slammed into the back of Kennedy.

The damage wasn't significant enough to prevent Harraka from making his Sprint Cup Series debut. But it was a short-lived race for the first driver to advance from NASCAR's diversity program into a Cup race ? Harraka spun and crashed his car six laps later.

Meanwhile, a parts failure caused Labonte to dump oil all over pit road before the race and he was forced to take his car to the garage for a quick repair. Labonte made it onto the track for the green flag, but his engine failed on the first lap.

"It blew up, dude," Labonte said on his radio. "Something in the bottom engine because it had no oil pressure."

Villeneuve had an issue shifting his gears and had to stay on pit road for a quick repair before trying to catch up to the field at the start of the race. He made it, but the problem wasn't completely corrected and he was back on pit road after 19 laps for more repairs.

Busch had back-to-back speeding penalties in yet another race that slipped away. He led 15 laps, lost the lead to former teammate Brad Keselowski, then was flagged for speeding when he went in for a scheduled pit stop. He had to return to pit road for a stop-and-go penalty and was flagged for speeding again.

It dropped Busch to 38th in the running order, from where he had to climb back to steal his strong finish.

His brother also had his share of problems. Kyle Busch was spun early in the race by Montoya to lose a ton of track position, then gave up everything he made up when he was caught speeding on pit road. He also spun at least two more times during the race.

Danica Patrick, thought to be a contender based on her strong runs in Nationwide Series road races, struggled all weekend to find speed and was done in by a flat rear tire just past the halfway point. The tire issue caused her to spin into a barrier and make multiple pit stops for repairs.

Pole-sitter Jamie McMurray never even led a lap under green as he was passed at the start by Ambrose, and his race took a big hit when he later ran off course with a tire problem and lost a lap.

Source: http://news.yahoo.com/martin-truex-jr-snaps-218-race-losing-streak-222553393.html

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Hatred between Sunnis, Shiites abounds in Mideast

In this Friday, June 7, 2013 photo, Iraqi worshippers attend a joint Sunni-Shiite Friday prayer in Baghdad, Iraq. Hatreds between Shiites and Sunnis are now more virulent than ever in the Arab world because of Syria's brutal civil war. Hard-line clerics and politicians on both sides have added fuel, depicting the fight as essentially a war of survival for their sect. (AP Photo/Hadi Mizban)

In this Friday, June 7, 2013 photo, Iraqi worshippers attend a joint Sunni-Shiite Friday prayer in Baghdad, Iraq. Hatreds between Shiites and Sunnis are now more virulent than ever in the Arab world because of Syria's brutal civil war. Hard-line clerics and politicians on both sides have added fuel, depicting the fight as essentially a war of survival for their sect. (AP Photo/Hadi Mizban)

FILE - This April 22, 2009 file photo, shows Iraqi women at the al-Sayda Zeinab shrine in southern Damascus, Syria. Hatreds between Shiites and Sunnis are now more virulent than ever in the Arab world because of Syria's brutal civil war. Hard-line clerics and politicians on both sides have added fuel, depicting the fight as essentially a war of survival for their sect. (AP Photo/Ola Rifai, File)

FILE - This June 14, 2012, file photo shows Syrian security forces at the site where a car bomb exploded near the shrine of Sayyida Zeinab, visible in the background, in a suburb of Damascus, Syria. Hatreds between Shiites and Sunnis are now more virulent than ever in the Arab world because of Syria's brutal civil war. Hard-line clerics and politicians on both sides have added fuel, depicting the fight as essentially a war of survival for their sect. (AP Photo/Bassem Tellawi, File)

FILE - In this Wednesday, Nov. 2, 2011 file photo, Muslim pilgrims visit the Hiraa cave, at the top of Noor Mountain on the outskirts of Mecca, Saudi Arabia. As Muslims from all over the world congregate for the annual hajj pilgrimage, some are defying the edicts of Saudi Arabia?s strict Wahhabi school of Islam by climbing al-Nour mountain in the hope of attaining spiritual favor. Hatreds between Shiites and Sunnis are now more virulent than ever in the Arab world because of Syria's brutal civil war. Hard-line clerics and politicians on both sides have added fuel, depicting the fight as essentially a war of survival for their sect. (AP Photo/Hassan Ammar, File)

In this Tuesday, June 4, 2013 photo, Shiite women pray at the Imam Moussa al-Kadhim shrine at Kazimiyah district of Baghdad, Iraq. Hatreds between Shiites and Sunnis are now more virulent than ever in the Arab world because of Syria's brutal civil war. Hard-line clerics and politicians on both sides have added fuel, depicting the fight as essentially a war of survival for their sect. (AP Photo/ Karim Kadim)

(AP) ? It's not hard to find stereotypes, caricatures and outright bigotry when talk in the Middle East turns to the tensions between Islam's two main sects.

Shiites are described as devious, power-hungry corruptors of Islam. Sunnis are called extremist, intolerant oppressors.

Hatreds between the two are now more virulent than ever in the Arab world because of Syria's civil war. On Sunday, officials said four Shiites in a village west of Cairo were beaten to death by Sunnis in a sectarian clash unusual for Egypt.

Hard-line clerics and politicians on both sides in the region have added fuel, depicting the fight as essentially a war of survival for their sect.

But among the public, views are complex. Some sincerely see the other side as wrong ? whether on matters of faith or politics. Others see the divisions as purely political, created for cynical aims. Even some who view the other sect negatively fear sectarian flames are burning dangerously out of control. There are those who wish for a return to the days, only a decade or two ago, when the differences did not seem so important and the sects got along better, even intermarried.

And some are simply frustrated that there is so much turmoil over a dispute that dates back to the death of the Prophet Muhammad in the 7th century.

"Fourteen centuries after the death of the prophet, in a region full of destruction, killing, occupation, ignorance and disease, you are telling me about Sunnis and Shiites?" scoffs Ismail al-Hamami, a 67-year-old Sunni Palestinian refugee in Gaza. "We are all Muslims. ... You can't ignore the fact that (Shiites) are Muslims."

Associated Press correspondents spoke to Shiites and Sunnis across the region. Amid the variety of viewpoints, they found a public struggling with anger that is increasingly curdling into hatred.

___

BACKGROUND

The Sunni-Shiite split is rooted in the question of who should succeed Muhammad in leading Muslims after his death in 632. Shiites say the prophet's cousin and son-in-law Ali was his rightful successor but was cheated when authority went to those the Sunnis call the four "Rightfully Guided Caliphs" ? Abu Bakr, Omar and Othman and, finally, Ali.

Sunnis are the majority across the Islamic world. In the Middle East, Shiites have strong majorities in Iran, Iraq and Bahrain, with significant communities in Lebanon, Yemen, Syria, Saudi Arabia, Kuwait and other parts of the Gulf.

Both consider the Quran the word of God. But there are distinctions in theology and religious practice between the two sects.

Some are minor: Shiites pray with their hands by their sides, Sunnis with their hands crossed at their chest or stomach.

Others are significant. Shiites, for example, believe Ali and a string of his descendants, the Imams, had not only rightful political authority after Muhammad but also held a special religious wisdom. Most Shiites believe there were 12 Imams ? many of them "martyred" by Sunnis ? and the 12th vanished, to one day return and restore justice. Sunnis accuse the Shiites of elevating Ali to the level of Muhammad himself ? incorrectly, since Shiites agree that Muhammad was the last of the prophets, a central tenet of Islam.

The bitter disputes of early Islam still resonate. Even secular-minded Shiite parents would never name their child after the resented Abu Bakr, Omar or Othman ? or Aisha, a wife of Muhammad, who helped raise a revolt against Ali during his Caliphate. When outgoing Iranian President Mahmoud Ahmadinejad visited Egypt earlier this year, the sheik of Al-Azhar, the bastion of Sunni theology, told him sharply that if the sects are to get along, Shiites must stop "insulting" the "companions of the prophet."

But only the most hard-core would say those differences are reason enough to hate each other. For that, politics is needed.

___

IRAQ

If Syria's war has raised the region's sectarian hatreds, the war in Iraq played a big role in unleashing them. After the U.S.-led invasion toppled Saddam Hussein in 2003, the long-oppressed Shiite majority there saw a chance to take power. Sunnis feared the repression would flip onto them. The result was vicious sectarian fighting that lasted until 2008: Sunni extremists pulled Shiite pilgrims from buses and gunned them down; Shiite militiamen kidnapped Sunnis, dumping their tortured bodies later.

ABDUL-SATTAR ABDUL-JABAR, 56, is a Sunni cleric who occasionally preaches at the prominent Abu Hanifa mosque in the Sunni-dominated Azamiyah neighborhood of Baghdad. Two of his sons were killed by Shiite militiamen. He blames the United States and Iran for Iraq's strife.

"Right from the beginning, the Americans were trying to create sectarian rifts," he said. "Iran is a country of regional ambitions. It isn't a Shiite country. It's a country with specific schemes and agendas."

Now he fears the strife is returning, and he blames the Shiite-dominated government.

"We feel the government does not consider us part of the Iraqi nation," he said. "There is no magical solution for this. If the Shiites are convinced to change their politicians, that would be a big help."

AHMED SALEH AHMED, 40, a Sunni, runs a construction company in Baghdad mainly employing Shiites. He is married to a Shiite woman. They live in the Azamiyah neighborhood and raise their two daughters and son as Sunnis.

Still, his wife prays with the small clay stone that Shiites ? but not Sunnis ? set in front of their prayer rugs. She often visits a Shiite shrine in another Baghdad district. Ahmed sometimes helps his wife's family prepare food for Shiite pilgrims during religious ceremonies. But he admits that there sometimes is tension between the families.

"We were able to contain it and solve it in a civilized way," Ahmed said.

Iraqis like to talk politics, he said, and "when things get heated, we tend to change the subject."

When their children ask about sectarian differences, "we do our best to make these ideas as clear as we can for them so they don't get confused," he said. "We try to avoid discussing sectarian issues in front of the children."

Ahmed believes sectarian tensions have been strained because people have abused the democratic ideas emerging from the Arab Spring.

Democracy "needs open-mindedness, forgiveness and an ability to understand the other," he said. "No human being is born believing in democracy. It's like going to school ? you have to study first. Democracy should be for people who want to do good things, not for those who are out for revenge."

HUSSEIN AL-RUBAIE, 46, a Shiite, was jailed for two years under Saddam. His Shiite-majority Sadriya district in Baghdad saw considerable bloodshed during the worst of the strife, and he fears it's returning.

"The whole region is in flames and we are all about to be burnt," he said. "We have a lot of people who are ignorant and easily driven by sectarian feelings."

He sees it among his friends, who include Sunnis. "My friends only whisper about sectarian things because they think it is a shame to talk about such matters," al-Rubaie said, "but I am afraid that the day might come when this soft talking would turn to fighting in the street."

___

LEBANON

Among some of Lebanon's Shiites, it's fashionable to wear a necklace with a medallion in the shape of the fabled double-bladed sword of Ali. It's a mark of community pride at a time when the Shiite group Hezbollah says the sect is endangered by Sunni extremists in the Syrian uprising.

During Lebanon's 1975-1990 civil war, the main fight was between Christians and Muslims. But in the past decade, the most dangerous divide has been between Shiites and Sunnis.

For much of Lebanon's existence, Shiites, who make up about a third of the population, were an impoverished underclass beneath the Christians and Sunnis, each roughly a third also. The Shiite resentment helped the rise of the guerrilla force Hezbollah, on whose might the community won greater power. Now, many Sunnis resent Hezbollah's political domination of the government. The 2005 assassination of Prime Minister Rafik Hariri, a Sunni, increased Sunni anger after Hezbollah members were blamed. Since then, both sides have clashed in the streets.

Syria's civil war has fueled those tensions. Lebanon's Sunnis largely back the mainly Sunni rebellion, while Shiites support President Bashar Assad's regime, which is dominated by his Alawite sect, an offshoot of Shiism. Hezbollah sent fighters to help Assad fight the rebels, enraging Sunnis region-wide.

RANIA, 51, is a Shiite Lebanese banking executive, married to a Sunni and living in Ras Beirut, one of the capital's few mixed neighborhoods.

When she married, at age 22, "I didn't even know what the difference between Sunnis and Shiites is."

Now she's inclined to support Hezbollah. While not a fan of the hard-line group, she believes that Hezbollah and Syria are targeted because of their stances against Israel. She said her husband is anti-Hezbollah and supports Syria's rebels.

Rania, who gave only her first name because she doesn't want to be stigmatized about her social, religious or marital status, said she doesn't talk politics with her husband to avoid arguments.

"I support one (political) side and he supports the other, but we've found a way to live with it," added Rania, who has a 22-year-old daughter.

She said education plays a big role. "I find that the people who make comments about it are the people who are just ignorant, and ignorance feeds hatred and stereotyping," she added.

KHALED CHALLAH is a 28-year-old Syrian Sunni businessman who has lived for years in Lebanon. He comes from a conservative, religious family but only occasionally goes to mosque. He said the only way he would be able to tell the difference between a Sunni mosque and a Shiite one would be if the cleric talked about Syria in the sermon.

"A Shiite imam would speak against the rebels, and call to resist them, and a Sunni sheik would talk against the government in Syria," he said.

He said he still doesn't understand the Shiites' emotional fervor over the battle of Karbala, in which Ali's son, Hussein, was killed by the armies of the Sunni Ummayad dynasty in the 7th century. Hussein's martyrdom is a defining trauma of their faith, deepening their feeling of oppression. Every year, Shiites around the world mark the battle with processions that turn into festivals of mourning, with men lashing or cutting themselves.

"It means much more to Shiites, this battle's memory, than to Sunnis," Challah said.

He said Sunnis "behave sometimes like they are the only Muslims."

Challah called this "very silly. Sunnis and Shiites come from the same root, they worship the same God."

___

IRAN

The Shiite powerhouse of the Middle East is home to a government led by Shiite clerics with oil wealth and a powerful Revolutionary Guard. Tehran has extended its influence in the Arab world, mainly through its alliance with Syria, Hezbollah in Lebanon and Hamas in the Palestinian territories. Iran has presented that alliance not as sectarian but as the center of "resistance" against Israel.

Sunni Saudi Arabia and other Gulf allies have been trying to stem Iran's influence, in part by warning of the spread of Shiism. Saudi Arabia's hard-line Wahhabi interpretation of Sunni Islam views Shiism as heresy.

REZA TAJABADI, a Shiite cleric in Tehran, blames the Wahhabis ? and the related ultra-conservative Salafi movement in Sunni Islam ? for stoking sectarian hatred.

"If Wahabis withdrew from creating differences, then Shiites and Sunnis will be able to put aside their minor differences, which are not considerable."

ABOLFATAH DAVATI, another Shiite cleric, points to the historical difference between the two sects. Since Sunnis have been dominant through history, Sunni clerics became subordinate to the rulers. The Shiite clergy, he said, has been independent of power.

"Sunni clerics backed rulers and justified their policies, like the killing of Imam Hussein. Even now, they put their rulers' decision at the top of their agenda," he said.

"In contrast, Shiites have not depended on government, so Sunnis cannot tolerate this and issue religious edicts against them. This increases rifts."

___

EGYPT

In a country where the Muslim population is overwhelmingly Sunni, many Egyptians know little about Shiites. The Shiite population is tiny and largely hidden ? so secretive that its numbers are not really known. But ultraconservative Salafis, many of whom view Shiites as infidels, have become more politically powerful and more vocal since the 2011 fall of autocrat Hosni Mubarak. They often preach against Shiism, warning it will spread to Egypt.

MONA MOHAMMED FOUAD is a rarity in Egypt: Her mother is an Iranian Shiite, her father an Egyptian Sunni. She considers herself Sunni.

"People are always surprised and shocked" when they find out her mother is Shiite, said Fouad, 23, who works for a digital marketing company. "But usually as soon as they know, they are very interested and they ask me many questions."

Fouad said her sister has heard work colleagues criticizing Shiites. In her fiance's office they distributed leaflets "telling people to beware of Shiite indoctrination," she added.

"People should read about Shiism. We make fun of foreigners who believe all Muslims are terrorists and we say they are ignorant, but we do the same thing to ourselves," Fouad said. "There is a difference in interpretation, a difference in opinion, but at the end of the day, we believe in the same things."

She told her Sunni fiance from the start that her mother is Shiite. "I told him to tell his family, so if they have any problem with that, we end it immediately."

ANAS AQEEL, a 23-year-old Salafi, spent the first 18 years of his life in Saudi Arabia, where he would sometimes encounter Shiites. "We didn't ever argue over faith. But they alienated me," he said.

"I once saw a Shiite in Saudi Arabia speaking ill of one of the companions of the prophet near his tomb. That one I had to clash with and expel him from the place," Aqeel said.

He worries about Shiites spreading their faith. While he said not all Shiites are alike, he added that "some of them deviate in the Quran and speak badly of the prophet's companions. If someone is wrong and ... he insists on his wrong concept, then we cannot call him a Muslim."

___

PALESTINIAN TERRITORIES

Palestinian Muslims are also almost all Sunnis. Their main connection to the Shiite world has Hamas' alliance with Iran. But those ties were strained when Hamas, which rules the Gaza Strip, broke its connections with Syria because of the civil war.

AHMED MESLEH, a 28-year-old blogger from the West Bank town of Ramallah, says he met Shiites on a trip to Lebanon and encounters them via Facebook. But some have de-friended him because of his online comments.

"If we take Shiites from a religious point of view, then we can describe Shiites as a sect that has gone astray from the true doctrine of Islam. I consider them a bigger threat to Muslims and Islam than Jews and Israel," Mesleh said.

He cited the Shiites' processions mourning Hussein's death, saying: "The way they whip themselves, it's irrational."

The Middle East conflict "is in its core a religious conflict. The Shiites want to destroy Islam. In Lebanon, they are the ones controlling the situation, and the ones who are causing the sectarian conflict."

ISMAIL AL-HAMAMI, a 67-year-old Palestinian refugee in Gaza's Shati camp, said politics not religion is driving sectarian tensions.

"In Gaza, Iran used to support the resistance with weapons. Now they support Assad. ... In Iraq, they (Shiites) executed Saddam Hussein, who was a Sunni, and they took over the country with the help of the Americans. Now they are working against America in Iran and Syria."

"So is that related to religion? It's all about politics."

The beneficiaries of sectarianism, he said, are "those who want to sell arms to both sides ... those who want to keep Arab and Muslim countries living in the dark. The beneficiaries are the occupation (Israel) and the people who sell us religious slogans."

"God knows who is right or wrong."

___

AP correspondents Adam Schreck and Qassim Abdul-Zahra in Baghdad, Barbara Surk and Zeina Karam in Beirut, Dalia Nammari in Ramallah and Ibrahim Barzak in Gaza City, Tony G. Gabriel and Mariam Rizk in Cairo and Nasser Karimi in Tehran contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-06-23-Mideast-Sunni-Shiite%20Voices/id-2335b2489bd942adb418ec55d636147d

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Archery programs gain popularity in schools ? Artesia News

TUPELO, Miss. (AP) ? Mississippi?s fastest growing sport doesn?t involve running or tackling or a ball.

Whether interest begins with 4-H programs or the movie ?The Hunger Games,? students are asking for archery in schools and trying out for the accuracy-driven sport.

With the growing popularity comes growing talent and three Northeast Mississippi schools ? each with archery programs only about two years old ? brought home state championships this year. Saltillo won the 5A championship, Hatley the 2A crown and Myrtle the 1A title.

Coaches Mark Davidson of Saltillo, Jennifer Taylor of Hatley and Keith Speck of Myrtle each give credit to students who were committed and gave their best in a stressful environment.

?I?m told archery is the fastest-growing sport in the state, if not in the nation,? said Davidson, who has been shooting competitively for more than 25 years.

Though some aspects of school shooting competitions are different from the traditional long bow and re-curve bow that he has used, shooters must use the same skills of shooting without a sight and using the fingers without an aid.

?Our program was in its second year,? Davidson said. ?We were able to win the state championship for the division and also the overall state championship back-to-back in our first two years because the kids were dedicated, put in their time and worked hard.?

Saltillo went on to compete in the nationals in Louisville, Ky., in May, where they came in 21st out of almost 10,000 shooters.

?We didn?t shoot to our potential there,? Davidson said. ?I think the big match pressure kind of got the best of them.?

Saltillo?s top scorer at the state competition was Landon Jones, with Caitlin Rigby joining him as a team leader. Rigby, 17, will be a senior in the fall and was Saltillo?s top female scorer. Her interest in archery started with 4-H.

?I?ve always been interested in sports and still shoot with 4-H too,? Rigby said. ?After I shoot it gets me excited to see most of my arrows in the yellow. It makes me so happy. The most advice I could give someone else is to take your time, not rush and have fun.?

Each school program has about 40 students overall, and the top 26 are able to attend state competition, 24 shooting and two alternates.

?What excites me about archery is that it?s a sport where girls can compete with guys,? said Hatley?s Taylor, a longtime bow hunter. ?It gets people who are not involved in other sports. They may think they?re not athletic enough for some other sport, but in this one all they have to have is accuracy.?

Two of Hatley?s team members graduated in May, but 24 will be returning. After tryouts for seventh- through 12th-graders, 40 students made the team.

Hatley?s top shooter, Braeden Eldridge, graduated in May.

?I got into archery because it was something new,? he said. ?I?d played baseball and tried other things, but when I tried this it stuck. The first year everybody was really young. I?ve always been around hunting, shotguns and been in the outdoors, but nobody else on the team shot bows or hunted. The next year they really stepped up, and when I shot bad they stepped in.?

Eldridge sees his archery career ending with high school as he moves on to college and hopes later the Marine Corps.

Myrtle, too, is fortunate to be bringing back all of its team except one graduate. Speck, a bow-hunter for more than 20 years, was tapped to start up the program just more than two years ago.

?There usually isn?t a lot of money for schools to start new programs, but we got two grants so the school was out very minimal cost to start it up,? he said.

Factors also mentioned by the other coaches ? that it?s a coed sport and that people who may not consider themselves to be athletic can represent their school in a sport ? also appeal to Speck.

The competition builds the student?s confidence, but the final outcome ?boils down to who is hot on that particular day,? Speck said. ?We were very fortunate the past two years to shoot our best score at the state tournament.?

Sixteen-year-old Kelsey Whitten, who will be a senior, has been his top shooter the past two years.

?I like archery because it?s something different,? Whitten said. ?I used to play softball a lot, then tried archery out and really liked it. I practice in my yard out back, make a target and do it until my arm starts hurting. I can?t really get tired of it.?

Whitten says that attitude of wanting to keep practicing and getting better is something she got from Speck.

?I probably wouldn?t be where I am now if the coach didn?t push us,? Whitten said. ?If we would miss practice or something, he?d impress on us how important it was, so I probably wouldn?t have achieved anything without him.?

Soon, though, archery shooters around Northeast Mississippi won?t need to fix a practice place in their own yards like Whitten does.

Bryan Ellis expects to open Mudcreek Archery, an indoor archery center in late June.

?There?s no other archery facility like it around here,? Ellis said. ?We were driving to Michie, Tenn., an hour and 15 minutes, and they only have a small range for one or two people to shoot. It?s nothing like what we?ve got.?

Mudcreek includes moving targets, pop-up targets, the computer simulation game, Techno Hunt, and more. With assistance from the Mississippi Department of Wildlife, Fisheries and Parks, they also will have the same equipment and targets schools use.?

?They have been very helpful to me, providing me with data about the number of shooting licenses they issue and other advice,? Ellis said. ?We?re self-titling it as ?Mississippi?s most advanced indoor archery range.? We?re going to hold non-school-affiliated tournaments that kids can enter so they have a place to go to shoot after school.?

Some youths also are introduced to archery through 4-H programs of the Mississippi State University Extension Service, with Alcorn County 4-H agent Tammy Parker as the district shooting sports coordinator.

?We have about 140 youths from 23 counties in the archery program,? Parker said. ?It has increased over the past several years. Alcorn County has 10 kids, but the only holdback is adult volunteers who will agree to go through the certification training. We could probably have 50 kids if we had enough adult volunteers to work with them.?

Archery in Mississippi Schools is a program supported by the Mississippi Wildlife, Fisheries and Parks Foundation, coordinating the implementation of archery programs in public and private schools.

?This is a continuation of the ongoing effort by the Foundation and the Mississippi Department of Wildlife, Fisheries and Parks to attract Mississippi youth into the out-of-doors and to support Mississippi schools in their effort to improve the physical condition of the youth and to provide youth with a pastime that they can utilize throughout their lives,? the Mississippi Archery In Schools website says.

Program coordinator Waldo Cleland resides in Columbia, and conducts training programs for school archery coaches as well as volunteer coaches.

Davidson retired from Saltillo at the close of school, but is excited about the new shooting facility where he?ll be able to keep using his skills.

?It?s exciting that the new archery complex will be very friendly to the school competition style of shooting, with the kind of bows and targets schools use,? he said. ?Any area student who wants to get in practice outside of school will have a place to go.?

___

Information from: Northeast Mississippi Daily Journal, http://djournal.com

This entry was posted on June 22, 2013, 8:02 am and is filed under Sports. You can follow any responses to this entry through RSS 2.0. Both comments and pings are currently closed.

Source: http://www.artesianews.com/2013/06/22/ap-news/sports-ap-news/archery-programs-gain-popularity-in-schools/

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Wing walker, pilot die in crash at Ohio air show

CINCINNATI (AP) ? A plane carrying a wing walker crashed Saturday at an air show and exploded into flames, killing the pilot and stunt walker instantly, authorities said.

The crash happened at around 12:45 p.m. at the Vectren Air Show at Dayton International Airport. No spectators were hurt.

A video posted on WHIO-TV shows the plane turn upside-down as the performer sits on top of the wing. The plane then tilts and crashes to the ground, exploding into flames as spectators screamed.

Ian Hoyt, 20, an aviation photographer and licensed pilot from Findlay, was at the show with his girlfriend. He told The Associated Press he was taking photos as the plane passed by and had just raised his camera to take another shot.

"Then I realized they were too low and too slow. And before I knew it, they hit the ground," he said.

He couldn't tell exactly what happened, but it appeared that the plane stalled and didn't have enough air speed, he said.

"I'm still shaking," Hoyt said. He said he had been excited to see the show because he'd never seen the scheduled performer ? wing walker Jane Wicker ? in action.

The names of those killed weren't immediately released, but a schedule on the event's website and the announcer at the show said Wicker was performing.

Airport spokeswoman Linda Hughes and Ohio State Highway Patrol Lt. Anne Ralston confirmed the deaths to the AP.

The show was canceled for the rest of the day, but organizers said events would resume Sunday. The National Transportation Safety Board said it is investigating the crash.

Another spectator, Shawn Warwick of New Knoxville, told the Dayton Daily News that he was watching the flight through binoculars.

"I noticed it was upside-down really close to the ground. She was sitting on the bottom of the plane," he said. "I saw it just go right into the ground and explode."

Wicker's website says she responded to a classified ad from the Flying Circus Airshow in Bealeton, Va., in 1990, for a wing-walking position, thinking it would be fun. Her full-time job was as a budget analyst for the Federal Aviation Administration, according to her website.

She told WDTN-TV in an interview this week that her signature move was hanging underneath the plane's wing by her feet and sitting on the bottom of the airplane while it's upside-down.

"I'm never nervous or scared because I know if I do everything as I usually do, everything's going to be just fine," she told the station.

Wicker wrote on her website that she had never had any close calls.

"What you see us do out there is after an enormous amount of practice and fine tuning, not to mention the airplane goes through microscopic care. It is a managed risk and that is what keeps us alive," she wrote.

In 2007, veteran stunt pilot Jim LeRoy was killed at the Dayton show when his biplane slammed into the runway while performing loop-to-loops and caught fire.

Organizers were presenting a trimmed-down show and expected smaller crowds at Dayton after the Air Force Thunderbirds and other military participants pulled out this year because of federal budget cuts.

The air show, one of the country's oldest, usually draws around 70,000 people and has a $3.2 million impact on the local economy. Without military aircraft and support, the show expected attendance to be off 30 percent or more.

___

Thomas reported from Philadelphia.

Source: http://news.yahoo.com/wing-walker-pilot-die-crash-ohio-air-show-191655523.html

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Sunday, June 23, 2013

Findings emphasize importance of vitamin D in pregnancy

June 22, 2013 ? Pregnant women pass low levels of vitamin D on to their babies at almost three times the extent previously thought, according to new research carried out at London's Kingston University.

While current studies suggest that around a fifth (19 per cent) of a newborn baby's supply or deficiency of vitamin D comes directly from its mother, experts from Kingston's School of Life Sciences have discovered that the figure is, in fact, almost three times as high at 56 per cent. The results have been revealed using a new measuring technique, developed in the laboratories at Kingston, which is able to examine eight different forms of vitamin D in greater detail for the first time.

The study, just published in Nutrition Journal, focused on 120 samples taken from 60 Greek mothers and their babies. The research was conducted with the Department of Obstetrics and Gynaecology at Aristotle University of Thessaloniki in Greece. Although the Mediterranean nation enjoys more hours of sunshine than the United Kingdom, the research revealed that many of the mothers had low levels of vitamin D, suggesting that what they ate was an equally important source.

Professor Declan Naughton, who headed the Kingston University research team, said the findings made it more important than ever that mothers-to-be received the key nutrient not only through sunlight but also through foods such as oily fish. "The impact that mothers deficient in vitamin D have on their babies' levels is a much bigger problem than we thought," Professor Naughton said. "Maintaining good supplies during pregnancy is clearly of vital importance for both mothers' and babies' long term health."

Lack of the vitamin in pregnant women has been linked to diabetes and increased rates of caesarean section births, while babies can be smaller than average. In children, the deficiency can cause rickets -- a soft bone disease.

Vitamin D plays an important role in maintaining good levels of calcium and phosphate which help form healthy bones and teeth. The two main forms are vitamin D3, which primarily comes from sunlight, and D2 which is found in a small number of foods including egg yolk, mushrooms, farmed salmon, mackerel, sardines and fortified bread and cereals. Processes in the body convert the vitamin into what is known as the circulating form -- the type commonly measured in routine blood tests -- followed by the active form -- the type that promotes calcium absorption, cell growth and immunity.

Professor Naughton and his team found that the type of vitamin D commonly measured in blood tests was not as reliable an indicator of vitamin D activity as other strands. They went on to discover that two epimer forms, previously thought to be unimportant, influenced levels in babies. "This shows the need for more accurate measurement to assess levels of vitamin D as well as the need to look more closely at its different forms," Professor Naughton said.

Further clinical studies would be required to examine the effectiveness of vitamin D supplements in pregnant women to see whether particular factors made it difficult for them to absorb the nutrient, Professor Naughton added.

The research forms part of wider investigations being conducted by Professor Naughton and his team into vitamin D's role in conditions including Alzheimer's disease, diabetes and multiple sclerosis.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/eecPir_52FI/130622154450.htm

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Plane with wing walker crashes at Ohio show; 2 die

DAYTON, Ohio (AP) ? A plane carrying a wing walker crashed Saturday at an air show and exploded into flames, killing the pilot and stunt walker instantly, authorities said.

Dayton International Airport spokeswoman Linda Hughes and Ohio State Highway Patrol Lt. Anne Ralston confirmed the deaths to The Associated Press.

The crash happened at around 12:45 p.m. at the Vectren Air Show near Dayton. No spectators were injured.

The show has been canceled for the remainder of the day. The names of those killed weren't immediately released, but a video posted on WHIO-TV showing the flight and crash identified the performer as wing walker Jane Wicker. A schedule posted on the event's website also had Wicker scheduled to perform.

The video shows the plane turn upside-down as Wicker sits on top of the wing. The plane then tilts and crashes to the ground, exploding into flames as spectators scream.

"All of a sudden I heard screaming and looked up and there was a fireball," spectator Stan Thayer of Wilmington, Ohio, told WHIO.

Another spectator, Shawn Warwick of New Knoxville, told the Dayton Daily News that he was watching the flight through binoculars.

"I noticed it was upside-down really close to the ground. She was sitting on the bottom of the plane," he said. "I saw it just go right into the ground and explode."

Wicker's website says she responded to a classified ad from the Flying Circus Airshow in Bealeton, Va., in 1990, for a wing-walking position, thinking it would be fun. Her full-time job was as a budget analyst for the Federal Aviation Administration, according to her website.

She told WDTN-TV in an interview this week that her signature move was hanging underneath the plane's wing by her feet and sitting on the bottom of the airplane while it's upside-down.

"I'm never nervous or scared because I know if I do everything as I usually do, everything's going to be just fine," she told the station.

Wicker wrote on her website that she had never had any close calls.

"What you see us do out there is after an enormous amount of practice and fine tuning, not to mention the airplane goes through microscopic care. It is a managed risk and that is what keeps us alive," she wrote.

In 2007, veteran stunt pilot Jim LeRoy was killed at the Dayton show when his biplane crashed and burned.

Organizers were presenting a trimmed-down show and expected smaller crowds at Dayton after the Air Force Thunderbirds and other military participants pulled out this year because of federal budget cuts.

The air show, one of the country's oldest, usually draws around 70,000 people and has a $3.2 million impact on the local economy. Without military aircraft and support, the show expected attendance to be off 30 percent or more.

Source: http://news.yahoo.com/plane-wing-walker-crashes-ohio-show-2-die-181933614.html

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Saturday, June 22, 2013

How to save battery life on your iPhone and iPad by tweaking Notification Center settings

How to save battery life on your iPhone and iPad by tweaking Notification Center settings

iPhone and iPad battery life is a precious commodity we just can't seem to get enough of. All of our social networks, email accounts, texts, and other apps want to send us notifications, which in turn, consumes more battery life. Sometimes tweaking settings in Notification Center can actually save quite a bit of battery life.

Here's what we recommend trying:

  1. Launch the Settings app from the Home screen of your iPhone or iPad.
  2. Tap on Notifications.
  3. FInd an app that frequently sends you notifications and tap on its name.
  4. Scroll down towards the bottom and you'll see an option for View in Lock Screen.
  5. Turn this option to Off for any apps that aren't important to be displayed on your Lock Screen.

By doing this, you'll still receive push notifications and you'll hear the tones, your screen just will not light up and they won't filter into your actual Lock Screen area. Upon unlocking your iPhone or iPad, checking Notification Center will still show them, they just won't appear in the Lock Screen portion. Basically, your screen doesn't light up every time you receive a notification from these apps any longer when the View on Lock Screen option is turned off. Less screen use equals better battery life. By doing this myself, I gained about an extra 15 to 25% battery life per day.

I've found this to be useful on apps I still want to know I'm receiving notifications for but don't necessarily need them on my Lock Screen such as Twitter and Facebook. I've also only get email notifications set up for VIP when it comes to the Lock Screen.

Try it out and let us know if you're getting better battery life!

    


Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/TduNFqMUJSY/story01.htm

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Wing walker, pilot die in crash at Ohio air show

Flames erupt from a plane after it crashed at the Vectren Air Show at the airport in Dayton, Ohio. The crash killed the pilot and stunt walker on the plane instantly, authorities said. (AP Photo/Dayton Daily News, Ty Greenlees)

Flames erupt from a plane after it crashed at the Vectren Air Show at the airport in Dayton, Ohio. The crash killed the pilot and stunt walker on the plane instantly, authorities said. (AP Photo/Dayton Daily News, Ty Greenlees)

This photo provided provided WHIO TV shows a plane after it crashed Saturday, June 22, 2013, at the Vectren Air Show near Dayton, Ohio. There was no immediate word on the fate of the pilot, wing walker or anyone else aboard the plane. No one on the ground was hurt. (AP Photo/WHIO-TV)

Map locates Vectren Air Show, Dayton, Ohio; 1c x 3 inches; 46.5 mm x 76 mm;

(AP) ? A plane carrying a wing walker crashed at an air show and exploded into flames Saturday, killing the pilot and stunt walker, authorities said.

The crash of the 450 HP Stearman happened at around 12:45 p.m. at the Vectren Air Show near Dayton in front of thousands of horrified spectators. No one else was hurt.

A video posted on WHIO-TV shows the plane turn upside-down as the performer sits on top of the wing. The plane then tilts and crashes to the ground, erupting into flames as spectators screamed.

Ian Hoyt, an aviation photographer and licensed pilot from Findlay, was at the show with his girlfriend. He told The Associated Press he was taking photos as the plane passed by and had just raised his camera to take another shot.

"Then I realized they were too low and too slow. And before I knew it, they hit the ground," he said.

He couldn't tell exactly what happened, but it appeared that the plane stalled and didn't have enough air speed, he said. He credited the pilot for steering clear of spectators and potentially saving lives.

"Had he drifted more, I don't know what would have happened," Hoyt said. He said he had been excited to see the show because he'd never seen the scheduled performer ? wing walker Jane Wicker ? in action.

On the video, the announcer narrates as the plane glides through the sky and rolls over while the stuntwoman perches on a wing.

"Now she's still on that far side. Keep an eye on Jane. Keep an eye on Charlie. Watch this! Jane Wicker, sitting on top of the world," the announcer said, right before the plane makes a quick turn and nosedive.

Federal records show that biplane was registered to Wicker, who lived in Loudon, Va. A man who answered the phone at a number listed for Wicker on her website said he had no comment and hung up.

One of the pilots listed on Wicker's website was named Charlie Schwenker. A post on Jane Wicker Airshows' Facebook page announced the deaths of Wicker and Schwenker and asked for prayers for their families.

A message left at a phone listing for Charles Schwenker in Oakton, Va., wasn't immediately returned.

Dayton International Airport spokeswoman Linda Hughes and Ohio State Highway Patrol Lt. Anne Ralston confirmed that a pilot and stunt walker had died but declined to give their names. The air show also declined to release their identities.

The show was canceled for the rest of the day, but organizers said events would resume Sunday and follow the previous schedule and normal operations. The National Transportation Safety Board said it is investigating the crash.

Another spectator, Shawn Warwick of New Knoxville, told the Dayton Daily News that he was watching the flight through binoculars.

"I noticed it was upside-down really close to the ground. She was sitting on the bottom of the plane," he said. "I saw it just go right into the ground and explode."

Than Tran, of Fairfield, said he could see a look of concern on the wing walker's face just before the plane went down.

"She looked very scared," he said. "Then the airplane crashed on the ground. After that, it was terrible, man ... very terrible."

Wicker's website says she responded to a classified ad from the Flying Circus Airshow in Bealeton, Va., in 1990, for a wing-walking position, thinking it would be fun. She was a contract employee who worked as a Federal Aviation Administration budget analyst, the FAA said.

She told WDTN-TV in an interview this week that her signature move was hanging underneath the plane's wing by her feet and sitting on the bottom of the airplane while it's upside-down.

"I'm never nervous or scared because I know if I do everything as I usually do, everything's going to be just fine," she told the station.

Wicker wrote on her website that she had never had any close calls.

"What you see us do out there is after an enormous amount of practice and fine tuning, not to mention the airplane goes through microscopic care. It is a managed risk and that is what keeps us alive," she wrote.

In 2011, wing walker Todd Green fell 200 feet to his death at an air show in Michigan while performing a stunt in which he grabbed the skid of a helicopter.

In 2007, veteran stunt pilot Jim LeRoy was killed at the Dayton show when his biplane slammed into the runway while performing loop-to-loops and caught fire.

Organizers were presenting a trimmed-down show and expected smaller crowds at Dayton after the Air Force Thunderbirds and other military participants pulled out this year because of federal budget cuts.

The air show, one of the country's oldest, usually draws around 70,000 people and has a $3.2 million impact on the local economy. Without military aircraft and support, the show expected attendance to be off 30 percent or more.

___

Thomas reported from Philadelphia. Associated Press writers Kerry Lester in Chicago and Randy Pennell in Philadelphia contributed to this report.

___

Online:

Raw video of crash: http://bit.ly/11Vf7JA

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-06-22-US-Air-Show-Crash/id-15e27eb9ec9b4eca97f7139f4005004a

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Changes in cell shape may lead to metastasis, not the other way around

June 21, 2013 ? A crucial step toward skin cancer may be changes in the genes that control cell shape, report a team of scientists from The Methodist Hospital Research Institute, the Institute of Cancer Research, London, and Harvard Medical School in an upcoming issue of Nature Cell Biology (now online).

Using automated high content screening and sophisticated computational modeling, the researchers' screening and analysis of tens of millions of genetically manipulated cells helped them identify more than a dozen genes that influence cell shape. Their work could lead to a better understanding of how cells become metastatic and, eventually, pinpoint new gene therapy targets for cancer treatment.

"We found that by altering the way the cells are grown to better mimic conditions in a living organism, gene expression could have a profound impact on cell shape," said Zheng Yin, the paper's lead author and a postdoctoral fellow at the Department of Systems Medicine and Bioengineering of The Methodist Hospital Research Institute (TMHRI). "This matters because many cancer biologists believe metastasis depends in part on the ability of cells to take on different shapes to escape their confines and spread to healthy tissue. We developed a method of identifying and analyzing the shapes of fruit fly cells, then validated and expanded the discoveries in mammal cancer cells.."

The scientists began their study in fruit fly immune cells called hemocytes. Under normal conditions, each hemocyte was found to take on just one of five distinct shapes about 98 percent of the time. In contrast to conventional wisdom, other shapes and "intermediate" forms were rare, suggesting genes that control cell shape behave more like light switches than teakettles coming to a slow boil. Genetic manipulation of these cells in a lab setting supported that view as well.

Next the group examined human and mouse melanoma cells, which also take on a variety of forms. The researchers identified seven genes that cause cells to take on an especially rounded form, or else an elongated form. One of these genes, PTEN, had a particularly strong impact. When turned off, virtually all cells became elongated or large and rounded, two shapes that can help cancerous cells escape confinement, travel blood vessels, and infiltrate healthy tissues. This information about PTEN is new, even though the gene was previously known to scientists as a tumor suppressor.

"By increasing the frequency of rounded and elongated cells this would provide metastatic cells with a survival advantage that is otherwise not gained by adopting only a single shape, or being highly plastic," said TMHRI Department of Systems Medicine and Bioengineering Chair Stephen T.C. Wong, Ph.D., P.E., who with Institute of Cancer Research, London, Fellow Chris Bakal, Ph.D., are the corresponding authors who oversaw the research.

Bakal added, "The cells have to become rounded to travel through the bloodstream or invade soft tissues such as the brain, but they take on an elongated shape to travel through harder tissues like bone. But until now, we knew hardly anything about how the cells assume either of these shapes and how they switch between the two."

Yin said he hopes data from the study will be useful to cell and developmental biologists who are interested in how and why many different kinds of animal cells change their shapes.

"I believe this dataset has great potential," he said. "We still saw three distinct shapes other than rounded and elongated, and a handful of cell populations enriched with intermediate shapes -- a lot of possibilities for hypothesis generation."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/MZnLMdSRuDo/130621141658.htm

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Bigbrain: An ultra-high resolution 3-D roadmap of the human brain

June 20, 2013 ? A landmark three-dimensional (3-D) digital reconstruction of a complete human brain, called the BigBrain, now for the first time shows the brain anatomy in microscopic detail -- at a spatial resolution of 20 microns, smaller than the size of one fine strand of hair -- exceeding that of existing reference brains presently in the public domain. The new tool is made freely available to the broader scientific community to advance the field of neuroscience.

Researchers from Germany and Canada, who collaborated on the ultra-high resolution brain model, present their work in the 21 June issue of the journal Science.

"The authors pushed the limits of current technology," said Science's senior editor Peter Stern about the international scientific effort. "Such spatial resolution exceeds that of presently available reference brains by a factor of 50 in each of the three spatial dimensions."

The sophisticated modern image processing methods reveal an unprecedented look at the very fine details of the human brain's microstructure, or cellular level. The anatomical tool will allow for three-dimensional cytoarchitectonic mapping of the human brain and serve as an atlas for small cellular circuit data, or single layers or sublayers of the cerebral cortex, explained the researchers.

Until recently, reference brains did not probe further than the macroscopic, or visible, components of the brain. Now, the BigBrain provides a resolution much finer than the typical 1 mm resolution from MRI studies.

The project "has been a tour-de-force to assemble images of over 7,400 individual histological sections, each with its own distortions, rips and tears, into a coherent 3-D volume," said senior author Dr. Alan Evans, a professor at the Montreal Neurological Institute at McGill University in Montreal, Canada. "This dataset allows for the first time a 3-D exploration of human cytoarchitectural anatomy."

Thin sections of a 65-year-old human female brain, which was embedded in paraffin wax, were cut with a special large-scale tool called a microtome. Then, the 20-micrometer thick histological sections were mounted on slides, stained to detect cell structures and finally digitized with a high-resolution flatbed scanner so researchers could reconstruct the high-resolution 3-D brain model. It took approximately 1,000 hours to collect the data. The resulting images reveal differences in the laminar pattern between brain areas.

The new reference brain, which is part of the European Human Brain Project, serves as a powerful tool to facilitate neuroscience research and "redefines traditional maps from the beginning of the 20th century," explained lead author Dr. Katrin Amunts from the Research Centre J?lich and director of the Cecile and Oskar Vogt Institute for Brain Research at the Heinrich Heine University D?sseldorf in Germany. "The famous cytoarchitectural atlases of the early 1900's were simplified drawings of a brain and were based on pure visual analysis of cellular organization patterns," added Dr. Amunts.

Because of the sheer volume of this dataset, the researchers say that there will be a push by those who want to use it to develop new and valuable tools for visualization, data management and analysis.

"We plan to repeat this process in a sample of brains so that we can quantify cytoarchitectural variability," said Dr. Evans. "We will also integrate this dataset with high-resolution maps of white matter connectivity in post-mortem brains. This will allow us to explore the relationship between cortical microanatomy and fiber connectivity," said Dr. Amunts.

"We are planning to integrate our receptor data of the human brain in the reference frame provided by the BigBrain," continued senior co-author Dr. Karl Zilles, who is senior professor of the J?lich Aachen Research Alliance and former director of the Cecile and Oskar Vogt Institute for Brain Research at the Heinrich Heine University D?sseldorf in Germany. "We will also transfer high-resolution maps of quantitative data on the regional and laminar distribution of native receptor complexes to the BigBrain. This will allow us to explore the relationship between cortical microanatomy and key molecules of neurotransmission."

The fine-grained anatomical resolution will allow scientists to gain insights into the neurobiological basis of cognition, language, emotions and other processes, according to the study. The researchers also stated that they plan to extract measurements of cortical thickness to gain insights into understanding aging and neurodegenerative disorders; create cortical thickness maps to compare data from in vivo imaging; integrate gene expression data from the Allen Institute; and generate a brain model with a resolution of 1 micron to capture details of single cell morphology.

Public access of the BigBrain dataset will be provided through the CBRAIN Portal with free registration, stated the researchers.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/lbH_-Te5gmQ/130620142928.htm

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Batavia Downs announces support for new gaming legislation | The ...

Press release:

Western Regional Off-Track Betting Corporation (WROTBC), owner/operator of Batavia Downs has pledged its support of the Upstate New York Gaming Economic Development Act and the referendum that will be put to the citizens of New York State in November.

?This legislation keeps Batavia Downs Gaming as a vital partner to state and local governments,? said Michael Kane, president and CEO of WROTBC and Batavia Downs Gaming. ?This act will allow us to continue providing good paying jobs and generating significant funding for schools and our municipalities. Governor Cuomo and the legislature recognize the significant contributions made by racetrack casinos in Western New York to state education funding and job creation.?

Source: http://thebatavian.com/howard-owens/batavia-downs-announces-support-new-gaming-legislation/38088

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